Tissue Therapies

CELL TYPE TESTING ::

Depending on cell type, VitroGro® can potentially deliver to the cell surface any growth factors that form a macromolecular complex with vitronectin and/or growth factor binding proteins.

Potential Multimeric VitroGro® components

Epidermal Growth Factor (EGF)

Fibroblast Growth Factor (FGF)

Transforming Growth Factor (TGF)

PDGF

Osteopontin

PAI-1

GM-CSF

Transferrin

VEGF

Collagen

VitroGro® TESTED CONTINUOUS CELL LINES

Long Term Serial Passaging

HaCAT keratinocytes

Short Term Assays

Human Embryonic Stem Cells

Human Corneal Epithelial

SaOS-2 Osteoblast-like

MCF-10A Breast Epithelial

T47D, MCF-7and MDA-MB 231 Breast Tumor

CHO-K1 Chinese Hamster Ovary

VERO

VitroGro® Tested Primary Cell Cultures:

Long Term Serial Passaging

Skin derived keratinocytes (human)

Corneal limbus derived keratinocyte progenitors (human)

Short Term Assays

Hair follicle outer root sheath derived keratinocyte progenitors (human)

Smooth muscle (porcine)

Umbilical vascular endothelial cells (human)

Alveolar bone derived osteoblast progenitors (human)

Bronchial epithelial (human)

In addition researchers are currently evaluating use of the complexes for the culture of dendritic cells for immunotherapy.

CELL TYPES IN THE PIPELINE FOR TESTING

293

NIH3T3

BHK-21

HeLa

Hybridoma

Chondrocytes

MDCK

Myoblast C2C12