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PUBLICATIONS

Rayment, E.A., Upton, Z. & Shooter, G.K. (2008) Increased matrix metalloproteinase-9 (MMP-9) activity observed in chronic wound fluid is related to the clinical severity of the ulcer. British Journal of Dermatology, in press, accepted 4/12/2007 (JIF: 3.334, Ranked 2 (of 39) in Dermatology, ISSN: 0007-0963)

Borg, D.J., Dawson, R.A., Leavesley, D.I., Upton, Z. & Malda, J. (2008) Functional and phentoptyic characterization of keratinocytes expanded using microcarrier culture. Journal of Biomedical Materials Research, Part A, in press, accepted 15/10/2007 (JIF: 2.497, Ranked 4 (of 42) in Biomedical Engineering, ISSN: 0021-9304)

Rayment E. A., Dargaville T.R., Shooter G.K., George G.A. & Upton, Z. (2008) Attenuation of protease activity in chronic wound fluid (CFW) with bisphosphonate-functionalised hydrogels. Biomaterials, 2008 Jan 31; [Epub ahead of print] (JIF:5.196, Ranked 1 (of 14) in Materials Science and Biomaterials, ISSN:0142-9612)

Upton, Z., Cuttle, L., Noble, A., Kempf, M., Topping, G., Hayes, M., Malda, J., Xie, Y., Mill, J., Leavesley, D., Kravchuk, O., Harkin, D.G. & Kimble, R. (2008) Vitronectin:growth factor complexes hold potential as a wound therapy approach. Journal of Investigative Dermatology, 2008 Jan 17; [Epub ahead of print] (JIF: 4.535, Ranked 1 (of 39) in Dermatology, ISSN: 0022-202X)

Hollier, B., Kricker, J.A., Leavesley, D.I. & Upton, Z. (2008) Substrate-bound IGF-I:IGFBP:Vitronectin-stimulated breast cell migration is enhanced by co-activation of the PI3-K/AKT pathway by alpha v-integrins and the IGF-1R. Endocrinology, 149(3): 1075-1090. [Epub ahead of print, Dec 13, 2007] (JIF: 5.236, ranked 13 (of 93) in Endocrinology and Metabolism, ISSN: 0013-7227)

Van Lonkhuyzen, D.R., Hollier, B., Shooter, G.K., Leavesley, D.I. & Upton, Z. (2007) A novel chimeric vitronectin:growth factor protein enhances human cell growth and migration through co-activation of growth factor receptors and vitronectin binding integrins. Growth Factors, 25: 295-308 (JIF:3.924, Ranked 22 (of 93) in Endocrinology and Metabolism, ISSN:0897-7194)

Denman, P., McElwain, D.W.S. Harkin, D.G. & Upton, Z. (2007) Mathematical modelling of spray-on skin with competitive epidermal clonal cell types. Bulletin of Mathematical Biology, 69: 157-79. (JIF: 1.720, Ranked 19 (of 64) in Biology, ISSN: 0092-8240)

Schwab, I.R., Johnson, N.T. & Harkin, D.G. (2006) Inherent risks associated with manufacture of bioengineered ocular surface tissue. Archives of Ophthalmology, 124(12): 1734-40. (JIF: 3.206, Ranked 6 (of 45) in Opthalmology, ISSN: 0003-9950)

Ainscough, S.L., Barnard, Z., Upton, Z. & Harkin, D. (2006) Vitronectin supports migratory responses of corneal epithelial cells to substrate bound IGF-I and HGF and facilitates serum-free cultivation. Experimental Eye Research, 83: 1505-14. (JIF: 2.776, Ranked 7 (of 45) in Ophthalmology, ISSN: 0014-4835)

Dawson, R.A., Upton, Z., Malda, J. & Harkin, D.G. (2006) IGF-I used in conjunction with IGFBP-5, EGF and vitronectin supports rapid preparation of cultured skin transplants under serum-free conditions. Transplantation, 81: 1668-1676. (JIF: 3.972, Ranked 3 (of 19) in Transplantation, ISSN: 0041-1337)

Harkin, D., Dawson, R. & Upton, Z. (2006) Optimised delivery of skin keratinocytes via aerosolization and suspension in fibrin tissue adhesive. Wound Repair and Regeneration, 14 ; 354-363. (JIF: 2.230, Ranked 10 (of 39) in Dermatology, ISSN: 1067-1927)

Topping, G., Malda, J., Dawson, R.A., & Upton, Z. (2006) Development and characterization of human skin equivalents and their potential application as a burn wound model. Primary Intention, 14: 14-21. (ISSN: 1323-2495)

Schleicher, I., Parker, T., Leavesley, D., Crawford, R., Upton, Z. & Xiao, Y. (2005) Surface modification of vitronectin and growth factors for human osteoblast culture. Tissue Engineering, 11: 1688-1698. (JIF: 3.725, ranked 23 (of 140) in Biotechnology and Applied Microbiology, ISSN: 1076-3279)

Leavesley, D.L, Harkin, D.G., McElwain, D.W.S., George, G. & Upton, Z. (2005) QUT eyes scar-less wound healing. Asia Pacific Biotech News, 9: 635-639. (ISSN: 0219-0303)

Hollier, B., Harkin, D., Leavesley, D.I. & Upton, Z. (2005) Responses of keratinocytes to substrate-bound vitronectin:growth factor complexes. Experimental Cell Research, 305: 221-232. (JIF: 3.777, Ranked 52 (of 156) in Cell Biology, ISSN: 0014-4827)

Leavesley, D., Harkin, D., Dawson, R., Gillies, P., Hollier, B., Ainscough, L., Hyde, C., Richards, S., Noble, A. & Upton, Z. (2004) Novel vitronectin:growth factor complexes for wound repair and tissue regeneration. Biotechnology and Agricultural Production. Eds Chang-Hung Chou & Shang-Shyng Yang. Dept Biochemistry, National University of Taiwan, Taipei. pp171-179. [ISBN: 957017482X]

Hyde, C.E., Hollier, B., Harkin, D., Anderson, A, & Upton, Z. (2004) Insulin-like growth factors (IGFs) and IGF-binding proteins bound to vitronectin enhance keratinocyte protein synthesis and migration. Journal of Investigative Dermatology, 122: 1198-1206. (JIF: 4.535, Ranked 1 (of 39) in Dermatology, ISSN: 0022-202X)

Kricker, J.A., Noble., A, Hyde., C.E., Firth, S.M., Herington, A.C. & Upton, Z. (2003) Structural and functional evidence for the interaction of IGFs and IGF-binding proteins with vitronectin. Endocrinology, 144: 2807-2815. (JIF: 5.236, ranked 13 (of 93) in Endocrinology and Metabolism, ISSN: 0013-7227)

Noble, A., Towne, C., Chopin, L., Leavesley, D.I. & Upton, Z. (2003) Insulin-like growth factor-II bound to vitronectin stimulates MCF7 breast cancer cell migration. Endocrinology, 144: 2417-2424. (JIF: 5.236, ranked 13 (of 93) in Endocrinology and Metabolism, ISSN: 0013-7227)



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